Stroke is the sudden onset of a neurological impairment, sometimes of crippling intensity. It is usually caused by occlusion of an artery that supplies the brain or spontaneous bleeding in the brain.
Stroke Community Forum
Support for patients with stroke, its warning signs, risk factors, prevention, complications. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.
Incidence of stroke in the elderly has dropped by 40% over the last 20 years
Jul 18, 2014
A new analysis of data from 1988-2008 has revealed a 40% decrease in the incidence of stroke in Medicare patients 65 years of age and older. This decline is greater than anticipated considering this population's risk factors for stroke, and applies to both ischemic and hemorrhagic strokes. Their findings are published in the July issue of The American Journal of Medicine.
Electrical stimulation of fastigial nucleus and cellular apoptosis in injured region
Jul 08, 2014
Previous studies have indicated that electrical stimulation of the cerebellar fastigial nucleus in rats may reduce brain infarct size, increase the expression of Ku70 in cerebral ischemia/reperfusion region, and decrease the number of apoptotic neurons. A new study finds anti-apoptotic activity of Ku70 in cytoplasm of rats subjected to electrical stimulation of cerebellar fastigial nucleus is related to colocalization of Ku70 with Bax.
Blocking key enzyme minimizes stroke injury
Jun 26, 2014
A drug that blocks the action of the enzyme Cdk5 could substantially reduce brain damage if administered shortly after a stroke, UT Southwestern Medical Center research suggests. The findings, reported in the June 11 issue of the Journal of Neuroscience, determined in rodent models that aberrant Cdk5 activity causes nerve cell death during stroke.
Migrating stem cells possible new focus for stroke treatment
May 27, 2014
A research group at Lund University in Sweden has revealed that stem cells known as pericytes, which are located in the outer blood vessel wall, appear to be involved in the brain reaction following a stroke. The findings show that the cells drop out from the blood vessel, proliferate, and migrate to the damaged brain area where they are converted into microglia cells, the brain's inflammatory cells.
Predicting which stroke patients will be helped—or harmed—by clot-busting treatment
May 20, 2014
Johns Hopkins researchers say they have developed a technique, which uses standard MRI scans to measure damage to the blood-brain barrier, that can predict—with 95% accuracy—which stroke victims will benefit from intravenous, clot-busting drugs and which will suffer dangerous and potentially lethal bleeding in the brain.
Study identifies new cause of brain bleeding immediately after stroke
Apr 17, 2014
While observing that blood-brain barrier function is rapidly impaired after a stroke (within 6 hours), researchers unexpectedly found that this early barrier failure is not due to the breakdown of tight junctions between blood vessel cells, as had previously been suspected. Instead, they reported dramatic increases in serum albumin flowing directly into brain tissue.
Study links severe sleep apnea to increased risk of stroke, cancer, and death
Apr 15, 2014
Results of a 20-year follow-up study show that people with moderate to severe obstructive sleep apnea were 4 times more likely to die, nearly 4 times more likely to have a stroke, 3 times more likely to die from cancer, and 2.5 times more likely to develop cancer. Results were adjusted for potential confounding factors such as body mass index, smoking status, total cholesterol, and blood pressure.
Bone marrow stem cells show promise in stroke treatment
Apr 10, 2014
Scientists at UC Irvine’s Sue & Bill Gross Stem Cell Research Center have published a study that finds the effects of mesenchymal stromal cells on functional stroke recovery are robust regardless of the dosage, time they were administered relative to stroke onset, or the method of administration.