Stroke and Cerebrovascular Diseases Center

Stroke is the sudden onset of a neurological impairment, sometimes of crippling intensity. It is usually caused by occlusion of an artery that supplies the brain or spontaneous bleeding in the brain.

Key Articles

Cerebral embolism
Cerebral venous thrombosis
Hypertensive intracerebral hemorrhage
Ischemic stroke
Lacunar infarction
Nontraumatic intracerebral hemorrhage
Subarachnoid hemorrhage
Vascular malformations

Management of Stroke

Cerebral revascularization other than carotid endarterectomy
Cerebral vasospasm: treatment
Gene therapy of cerebrovascular disease
Stroke therapy
Stroke: supportive care

Frequently Occurring Problems Associated with Stroke

Amaurosis fugax
(Transient monocular blindness)
Carotid bruit
Carotid endarterectomy for asymptomatic stenosis: can we predict which patients will do well?
Depression after stroke
Headache associated with ischemic cerebrovascular disease
Management of blood pressure after acute stroke
Medical complications of stroke
Patent foramen ovale
The definition and appropriate evaluation of transient ischemic attack
TIAs (carotid)
Vascular cognitive impairment

Related Articles

Carotid endarterectomy for asymptomatic stenosis: how are we doing in practice?
Causes of death by level of dependency after ischemic stroke
Comparison of hemorrhagic and ischemic strokes
Complications of chiropractic spinal manipulation
Deaths after chiropractic spinal manipulation
Detection of paroxysmal atrial fibrillation in patients with cerebral ischemia
Drug-induced cerebrovascular disease
Guidelines for vascular risk factor reduction for secondary prevention of ischemic stroke
Hemorrhagic transformation of ischemic stroke
Hormonal contraception and stroke
Intracerebral hemorrhage due to thrombolytic therapy
Pregnancy and stroke
Risk stratification after transient ischemic attack using the ABCD2 prediction rule
Sleep and stroke
Spinal cord ischemia
Stroke associated with drug abuse
Stroke associated with sickle cell disease
Stroke in young adults
Vascular risk factors and progression of Alzheimer disease
What is the current status of patent foramen ovale and stroke?
White matter abnormalities in the brain

External Resources

AAN Guidelines: Brain Injury and Brain Death
AAN Guidelines: Stroke and Vascular Neurology
Cedars-Sinai Stroke Program: Cerebral Hemorrhages
Clinical Trials: Brain Injury
Clinical Trials: Cerebral Infarction
Clinical Trials: Intracerebral Hemorrhage
European Society of Hypertension
FDA Advisory: Angiotensin Receptor Blockers: Cancer Risk Safety Review
Guideline: Head Injury - National Collaborating Centre for Acute Care (U.K.)
Guidelines and Consensus Statements: The Internet Stroke Center
Guidelines: The Brain Attack Coalition
Intracerebral Hemorrhage: The Internet Stroke Center
Intracranial Hypertension Research Foundation
Society for Hypertension
Stroke Scales and Clinical Assessment Tools

Communities

Stroke Community Forum
Support for patients with stroke, its warning signs, risk factors, prevention, complications. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.

News

Applying new cholesterol guidelines to a patient population reduces heart attacks, strokes
Aug 19, 2014
A study by UT Southwestern researchers identified Dallas Heart Study participants in the 30- to 65-year rage range who would have newly qualified for statin use under the cholesterol guidelines introduced in 2013 by the American College of Cardiology and the American Heart Association. They found that the recently introduced cholesterol guidelines would significantly reduce new cardiovascular events when compared to treatment based on previous cholesterol guidelines.
Experiencing atrial fibrillation while hospitalized for surgery linked with increased risk of stroke
Aug 13, 2014
In a study that included 1.7 million patients undergoing inpatient surgery, experiencing atrial fibrillation while hospitalized was associated with an increased long-term risk of ischemic stroke, especially following noncardiac surgery, according to a study in the August 13 issue of JAMA.
Monitoring pulse after stroke may prevent a second stroke
Jul 24, 2014
New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of having a second stroke. The study is published in Neurology®.
Incidence of stroke in the elderly has dropped by 40% over the last 20 years
Jul 18, 2014
A new analysis of data from 1988-2008 has revealed a 40% decrease in the incidence of stroke in Medicare patients 65 years of age and older. This decline is greater than anticipated considering this population's risk factors for stroke, and applies to both ischemic and hemorrhagic strokes. Their findings are published in the July issue of The American Journal of Medicine.
Electrical stimulation of fastigial nucleus and cellular apoptosis in injured region
Jul 08, 2014
Previous studies have indicated that electrical stimulation of the cerebellar fastigial nucleus in rats may reduce brain infarct size, increase the expression of Ku70 in cerebral ischemia/reperfusion region, and decrease the number of apoptotic neurons. A new study finds anti-apoptotic activity of Ku70 in cytoplasm of rats subjected to electrical stimulation of cerebellar fastigial nucleus is related to colocalization of Ku70 with Bax.
Blocking key enzyme minimizes stroke injury
Jun 26, 2014
A drug that blocks the action of the enzyme Cdk5 could substantially reduce brain damage if administered shortly after a stroke, UT Southwestern Medical Center research suggests. The findings, reported in the June 11 issue of the Journal of Neuroscience, determined in rodent models that aberrant Cdk5 activity causes nerve cell death during stroke.
Migrating stem cells possible new focus for stroke treatment
May 27, 2014
A research group at Lund University in Sweden has revealed that stem cells known as pericytes, which are located in the outer blood vessel wall, appear to be involved in the brain reaction following a stroke. The findings show that the cells drop out from the blood vessel, proliferate, and migrate to the damaged brain area where they are converted into microglia cells, the brain's inflammatory cells.
Predicting which stroke patients will be helped—or harmed—by clot-busting treatment
May 20, 2014
Johns Hopkins researchers say they have developed a technique, which uses standard MRI scans to measure damage to the blood-brain barrier, that can predict—with 95% accuracy—which stroke victims will benefit from intravenous, clot-busting drugs and which will suffer dangerous and potentially lethal bleeding in the brain.
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