Parkinson disease (PD) is characterized by abnormalities of posture, balance, and mobility, accompanied by muscular rigidity and course tremor of the forearms. Tremor may be lacking in other forms of parkinsonism. Disorders in this category are referred to as extrapyramidal disorders. PD is sometimes spelled as (Parkinson's disease and Parkinsons disease).
Parkinsons Community Forum
Support for patients with Parkinson disease and related neurological disorders. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.
Team uses exosomes to deliver Parkinson meds directly to brain
May 05, 2015
Researchers at the University of North Carolina at Chapel Hill have used exosomes from immune cells and successfully loaded them with the enzyme catalase, a potent antioxidant that counters the neuron-killing inflammation responsible for Parkinson and other degenerative neurologic disorders. Their work was published in the Journal of Controlled Release.
How deep-brain stimulation reshapes neural circuits in Parkinson disease
Apr 12, 2015
UC San Francisco scientists have discovered a possible mechanism for how deep-brain stimulation exerts its therapeutic effects. The new research, published online today in Nature Neuroscience, reveals that deep-brain stimulation keeps Parkinson disease symptoms in check by reducing excessive synchronization of brain activity in the motor cortex.
Mood, anxiety disorders common in Tourette patients, emerge at a young age
Mar 10, 2015
A new study of Tourette syndrome led by researchers from UC San Francisco and Massachusetts General Hospital has found that nearly 86% of patients who seek treatment for Tourette syndrome will be diagnosed with a second psychiatric disorder during their lifetimes, and that nearly 58% will receive 2 or more such diagnoses.
New information on Parkinson disease: GDNF not needed by midbrain dopamine system
Mar 04, 2015
A new study proves that the complete absence of glial cell-derived neurotrophic factor (GDNF) does not cause significant changes to the amount or function of dopamine neurons, reversing the findings of an article published in Nature Neuroscience in 2008.
Levodopa-carbidopa intestinal gel may prove more effective for long-term Parkinson treatment
Feb 27, 2015
After long-term treatment with oral medications for Parkinson disease, about most patients experience dyskinesias, end-of-dose wearing off, and fluctuations in "On/Off" states. Continuous dosing via a levodopa-carbidopa intestinal gel (LCIG) directly into the small intestine may be the key to reducing the motor complications associated with long-term levodopa use. In the current issue of the Journal of Parkinson's Disease, researchers report on the safety and efficacy of LCIG therapy over a 1-year period.
Could eating peppers prevent Parkinson disease?
May 09, 2013
New research reveals that Solanaceae—a flowering plant family with some species producing foods that are edible sources of nicotine—may provide a protective effect against Parkinson disease. The study appearing today in Annals of Neurology, suggests that eating foods that contain even a small amount of nicotine, such as peppers and tomatoes, may reduce risk of developing Parkinson disease.
Seeing a neurologist helps people with Parkinson disease live longer
Aug 11, 2011
People with Parkinson disease who go to a neurologist for their care are more likely to live longer, less likely to be placed in a nursing home, and less likely to break a hip than people who go to a primary care physician, according to a study published in the August 10, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.
REM sleep behavior disorder is a risk factor for Parkinson disease
Jul 29, 2011
A new study used brain SPECT to conclude that the levels of dopamine in the brain are quickly lowering over the years in patients with REM sleep behavior disorder.