Neuropathy Center

Neuropathies are disorders that affect one or more peripheral nerves causing weakness, clumsiness and disturbances of sensation and coordination. They include mononeuropathies, polyneuropathies, peripheral neuropathies, mononeuritis multiplex, sensory neuropathies, motor neuropathies, and sensorimotor neuropathies.

Overview Articles

Acute autonomic neuropathies
Chemotherapy-induced neuropathies
Clinical evaluation of peripheral neuropathies
Drug-induced neurologic disorders
Drug-induced neuropathies
Mitochondrial disorders
Neuromuscular pathology: overview
Nutrition-related peripheral neuropathies
Small fiber neuropathies
Toxic peripheral neuropathies
Vasculitic neuropathies

Specific Non-Hereditary Neuropathies

Acute inflammatory demyelinating polyradiculoneuropathy
(Guillain-Barre syndrome)
Arsenic neuropathy
Bell palsy
Brachial neuritis
Carpal tunnel syndrome
Complex regional pain syndrome
(Causalgia; reflex sympathetic dystrophy)
Critical illness myopathy and polyneuropathy
Diabetic neuropathies
Lead neuropathy
Mercury neuropathy
Paraneoplastic sensory neuronopathy
Peroneal neuropathy
Radial neuropathy
(Saturday night palsy)
Radiation plexopathy
Sciatic neuropathy
Ulnar neuropathy at the elbow
Uremic neuropathy

Hereditary Polyneuropathies

The following disorders may be early manifestations of multiple sclerosis or may never progress beyond their initial manifestations.
Adrenoleukodystrophy
Choreoacanthocytosis
Hereditary motor and sensory neuropathy 1A
Hereditary neuropathy with predisposition to pressure palsy
Neuroacanthocytosis

Related Articles

Treatment Information

Autonomic neuropathy: treatment
Immunotherapy in neuromuscular disorders
Neuropathic pain: treatment
Peripheral neuropathies: treatment with neurotrophic factors
Rehabilitation of peripheral nerve diseases

External Resources

AAN Guideline: Botulinum Neurotoxin in the Treatment of Autonomic Disorders and Pain
AAN Guidelines: Neuromuscular Disorders
Clinical Trials: Peripheral Neuropathy
Clinical Trials: Small Fiber Neuropathy
NGC Guideline: Carpal Tunnel Syndrome
NGC Treatment Guideline: Complex Regional Pain Syndrome (3rd Edition)
NINDS Guillain-Barre Syndrome Information Page
Video: Sensory Assessment - Discriminatory Sensations
Video: Sensory Assessment - Vibration and Position

Communities

Neuropathy Community Forum
Support for patients with peripheral neuropathy and related neurological disorders. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.

News

Mice point to a therapy for Charcot-Marie-Tooth disease
Aug 02, 2011
VIB researchers have developed a mouse model for Charcot-Marie-Tooth neuropathy. They also found a potential therapy for this incurable disease. The treatment not only halted the damage to the nerves and the atrophy of the muscles, it even succeeded in reversing the symptoms.
Diabetes drug may help prevent neuropathic pain
Jul 26, 2011
The diabetes drug rosiglitazone (Avandia) can control inflammation leading to nerve damage and abnormal pain responses, suggests a paper in the August issue of Anesthesia & Analgesia.
Breathing restored after spinal cord injury in rodent model
Jul 13, 2011
Researchers at Case Western Reserve University School of Medicine bridged a spinal cord injury and biologically regenerated lost nerve connections to the diaphragm, restoring breathing in an adult rodent model of spinal cord injury. The work, which restored 80% to more than 100% of breathing function, will be published in the online issue of the journal Nature July 14.
Flavonoids could represent 2-fisted assault on diabetes and nervous system disorders
Jun 28, 2011
A recent study from scientists at the Salk Institute for Biological Studies suggests that a strawberry a day (or more accurately, 37 of them) could keep not just one doctor away, but an entire fleet of them, including the neurologist, the endocrinologist, and maybe even the oncologist.
To fix diabetic nerve damage, blood vessels and support cells may be the real targets of treatment
Jun 24, 2011
Blood vessels and supporting cells appear to be pivotal partners in repairing nerves ravaged by diabetic neuropathy, and nurturing their partnership with nerve cells might make the difference between success and failure in experimental efforts to regrow damaged nerves, Johns Hopkins researchers report in a new study.
Mystery ingredient in coffee boosts protection against Alzheimer disease
Jun 22, 2011
A new Alzheimer mouse study by researchers at the University of South Florida has found that a yet unidentified component of coffee interacts with the beverage's caffeine to boost blood levels of a critical growth factor that seems to fight off the Alzheimer disease process.
Free DVD and guidebook answer questions for patients with diabetic nerve pain
May 06, 2011
Actor Jerry Mathers is the host of the American Academy of Neurology Foundation’s latest patient education video and guidebook, Diabetic Nerve Pain: A Guide for Patients and Families. The video and guidebook are aimed at answering important questions for people who suffer from nerve pain due to diabetes and can be viewed and downloaded for free.
AAN issues new guideline on best treatments for diabetic nerve pain
Apr 15, 2011
The American Academy of Neurology has issued a new guideline on the most effective treatments for diabetic nerve pain. The guideline is published in the April 11, 2011, online issue of Neurology®.
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