Multiple Sclerosis Center

Multiple sclerosis is a highly variable disorder that usually presents with recurrent, painless episodes of neurologic symptoms at 15 to 50 years of age.

Comprehensive Article

Multiple sclerosis
This comprehensive clinical reference includes information on many different areas of MS, including:

Key Articles

Early Manifestations of Multiple Sclerosis

The following disorders may be early manifestations of multiple sclerosis or may never progress beyond their initial manifestations.

Unusual Manifestations of Multiple Sclerosis

Disorders Sometimes Confused with MS

The manifestations of multiple sclerosis are very variable. There are therefore many other disorders that can be misdiagnosed as multiple sclerosis. The greatest impostor is neuromyelitis optica.

Treatment Information

External Resources

AAN Guideline: Neutralizing Antibodies to Interferon-beta: Clinical and Radiographic Impact
AAN Guidelines: Multiple Sclerosis
EFNS Guidelines On the Use of Neuroimaging In the Management Of Multiple Sclerosis
FDA Advisory: Natalizumab - Update of Healthcare Professional Information
MS Society of Canada
MS Society of Great Britain and Northern Ireland
Multiple Sclerosis Association of America
Multiple Sclerosis International Federation
National MS Society: Professional Resource Center
NICE Guideline: Management of Multiple Sclerosis in Primary and Secondary Care
Video: Multiple sclerosis - histopathology spinal cord
Video: Neuromyelitis optica
Video: Patient Guide to Managing MS


Multiple Sclerosis Community Forum
Support for patients with multiple sclerosis and related neurological disorders. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.


Research identifies how vitamin D combats multiple sclerosis
Aug 16, 2011
A study published in the journal Molecular and Cellular Biology finds that vitamin D directly terminates the production of a disease-causing protein.
Researchers uncover genes linked to multiple sclerosis
Aug 10, 2011
An international team of scientists has identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of an important and very debilitating neurologic disease.
Newly discovered B cells suggest why women suffer more autoimmune disease
Aug 04, 2011
Researchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease. The findings also suggest why diseases such as lupus, multiple sclerosis, and rheumatoid arthritis strike women more frequently than men.
Myelin influences how brain cells send signals
Jul 22, 2011
The development of a new cell-culture system that mimics how specific nerve cell fibers in the brain become coated with protective myelin opens up new avenues of research about multiple sclerosis. Initial findings suggest that myelin regulates a key protein involved in sending long-distance signals.
Multiple sclerosis drugs help, but come at high cost
Jul 21, 2011
A new study examining the cost-effectiveness of drugs to treat multiple sclerosis in the United States finds that the health gains from these drugs come at a very high cost compared to basic therapy to control the symptoms of multiple sclerosis and compared to treatments for other chronic diseases. The research is published in the July 20, 2011, online issue of Neurology.
Breastfeeding does not protect against multiple sclerosis relapses
Jul 07, 2011
New research finds breastfeeding doesn’t appear to protect against multiple sclerosis relapses, despite previous studies suggesting there may be a protective role.
Study finds pregnancy safe in multiple sclerosis
Jun 27, 2011
Canadian researchers have found that maternal multiple sclerosis is generally not associated with adverse delivery outcomes or risk to offspring.
Group therapy helps multiple sclerosis patients cope with depression
Jun 13, 2011
Researchers from the United Kingdom have found that multiple sclerosis sufferers who attended group therapy sessions had fewer problems with anxiety and depression, the impact of the disease on their daily lives was reduced, and their quality of life improved.
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