Epilepsy and Seizures Center

Epilepsy is characterized by recurrent episodes of loss or alteration of consciousness, posturing, and/or muscular jerking, usually lasting from seconds to minutes.

Overview

Epilepsy

Adult-Onset

Alcohol withdrawal seizures
Drug-induced seizures
Generalized tonic-clonic status epilepticus
Mesial temporal lobe epilepsy with hippocampal sclerosis
Posttraumatic epilepsy
Secondarily generalized tonic-clonic seizures

Childhood Seizures

Absence status epilepticus
(Petit mal status)
Atypical absences
Childhood absence epilepsy
(Petit mal seizures)
Febrile seizures
Neonatal seizures
Seizures presenting in childhood
Typical absences

Related Articles

Epilepsy quality-of-care measures
Epilepsy: treatment in developing countries
Fetal anticonvulsant syndrome
Impact of sleep on epileptic manifestations
Migraine and epilepsy
Sleep and epilepsy

Symptoms that May be Confused with Seizures

Benign paroxysmal vertigo of childhood
Breath-holding spells
Drop attacks
Eye closure and other signs of psychogenic nonepileptic seizures
Hyperventilation syndrome
Neurocardiogenic syncope
(Vasovagal syncope; fainting)
Periodic limb movements
Psychogenic seizures
(Pseudoseizures; nonepileptic seizures)
Syncope
Transient global amnesia

Antiepileptic Drugs

Carbamazepine
Diazepam
Fosphenytoin
Gabapentin
Lacosamide
Lamotrigine
Levetiracetam
Oxcarbazepine
Pharmacological treatment of epilepsy in adolescents and adults
Phenytoin
Pregabalin
Primidone
Tiagabine
Topiramate
Valproic acid
Vigabatrin
Zonisamide

Non-Drug Treatments

Epilepsy surgery in adults
Epilepsy surgery in children
Ketogenic diet in the treatment of epilepsy
Vagus nerve stimulation

External Resources

AAN Guidelines: Epilepsy
Epilepsy Foundation
Epilepsy.com: Surgery
ILAE Antiepileptic Drug Database
International League Against Epilepsy
National Society for Epilepsy
NICE Guidelines: Epilepsy
NINDS Epilepsy Information Page

Communities

Epilepsy Community Forum
Support for patients with epilepsy and seizures and related neurological disorders. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.

News

Reverse engineering epilepsy’s ‘miracle’ diet
May 23, 2012
For decades, neurologists have known that a diet high in fat and extremely low in carbohydrates can reduce epileptic seizures that resist drug therapy. But how the diet worked, and why, was a mystery. Now, researchers have proposed an answer, linking resistance to seizures to a protein that modifies cellular metabolism in the brain. The research, to be published in the May 24th issue of the journal Neuron, may lead to the development of new treatments for epilepsy.
Pediatric epilepsy impacts sleep for the child and parents
May 17, 2012
Researchers have determined that pediatric epilepsy significantly impacts sleep patterns for the child and parents. According to the study available in Epilepsia, sharing a room or co-sleeping with their child with epilepsy decreases the sleep quality and prevents restful sleep for parents.
Study raises questions about use of antiepilepsy drugs in newborns
May 11, 2012
A brain study in infant rats demonstrates that the antiepilepsy drug phenobarbital stunts neuronal growth, which could prompt new questions about using the first-line drug to treat epilepsy in human newborns.
Evidence of familial vulnerability for epilepsy and psychosis
May 02, 2012
Epidemiological study finds evidence that epilepsy and psychotic illness may cluster within some families, and indicates that these disorders may be more closely linked than previously thought.
Gauging seizures’ severity
Apr 27, 2012
In this week's issue of the journal Neurology, researchers at MIT and 2 Boston hospitals provide early evidence that a simple, unobtrusive wrist sensor could gauge the severity of epileptic seizures as accurately as electroencephalograms (EEGs) do—but without the ungainly scalp electrodes and electrical leads.
New medication offers hope to patients with frequent, uncontrollable seizures
Apr 19, 2012
A new type of antiepilepsy medication that selectively targets proteins in the brain that control excitability may significantly reduce seizure frequency in people whose recurrent seizures have been resistant to even the latest medications, new Johns Hopkins-led research suggests.
Symptoms that mimic epilepsy linked to stress, poor coping skills
Apr 10, 2012
Based on their clinical experience and observations, a team of Johns Hopkins physicians and psychologists say that more than one third of the patients admitted to The Johns Hopkins Hospital's inpatient epilepsy monitoring unit for treatment of intractable seizures have been discovered to have stress-triggered symptoms rather than a true seizure disorder.
Shedding new light on neural imaging research
Apr 03, 2012
Using cutting-edge illumination technology, researchers have developed a new cost-effective neural imaging system that allows researchers to make much more complex maps of the brain than are currently available. The team's initial findings, released this week in Biomedical Optics Express, demonstrate that this new technology may one day transform the way researchers view the human brain.
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