Brain Tumors and Cancer of the Nervous System Center

Brain tumors are benign or cancerous growths in the brain. Nervous system cancers include malignancies that arise in or spread to the brain, spinal cord, spinal fluid, nerve roots, and nerves. Benign tumors may also arise in the spinal cord, nerve roots, and nerves.

Communities

Brain Tumor Community Forum
Support for patients with benign and malignant tumors arising or affecting the brain, spinal cord, spinal fluid, nerve roots or nerves. Discussions among patients, families, caregivers and professionals on topics related to diagnosis, treatment, and activities of daily living.

News

Study reveals effects of chemoradiation in brains of glioblastoma patients
Aug 18, 2015
A new study - the first to examine the effects of combined radiation and chemotherapy on the healthy brain tissue of glioblastoma patients - reveals not only specific structural changes within patients' brains, but also that the effect of cancer therapy on the normal brain appears to be progressive and continues even after radiation therapy has ceased.
Targeted therapy shows effectiveness against a subtype of medulloblastoma
Jul 30, 2015
Vismodegib, a targeted therapy already used to treat advanced skin cancer, is also effective against the most common subtype of the brain tumor medulloblastoma in adults and should be considered for treatment of newly diagnosed patients, according to research led by St Jude Children’s Research Hospital.
Nanotechnology identifies brain tumor types through MRI ‘virtual biopsy’ in animal studies
May 25, 2015
Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through "virtual biopsies" and then attack the molecular structure of the disease. If laboratory research with mice is borne out in human studies, results could be used to deliver nano-scale drugs that can distinguish and fight tumor cells in the brain without resorting to surgery.
Anti-CD47 treatment shows promise in fight against glioblastoma multiforme
May 04, 2015
Results of a new study indicate that in vitro disruption of the CD47-SIRPa signal induced a response from both M1 and M2 macrophages; however, the rate and responsiveness of phagocytosis by M1 macrophages was consistently greater. In addition, phenotypic evaluation of local macrophages surrounding transplanted GBM tissue in mice suggests that anti-CD47 treatment promotes a larger local M1 population.
Scientists observe deadly dance between nerves and cancer cells
Apr 29, 2015
Study findings appearing in Nature Communications challenge conventional wisdom about perineural invasion, which holds that cancer cells are marauders that invade nerves through the path of least resistance. This study instead discovered that perineural invasion is actually a much more intricately choreographed biochemical give-and-take between the nerves and the cancer cells.
Researchers identify protein pathway involved in brain tumor stem cell growth
Feb 26, 2015
Moffitt Cancer Center researchers are one step closer to understanding glioblastoma development following the identification of a key protein signaling pathway involved in brain tumor stem cell growth and survival.
New brain tumor gene identified for meningiomas
Aug 08, 2011
The causes of brain tumors have been hard to discern in most cases. But an international collaboration of researchers have discovered a genetic variation--a gene variant that is close to MLLT10 on chromosome 10--that increases the risk of meningiomas.
Scientists map genes for oligodendroglioma
Aug 05, 2011
Johns Hopkins Kimmel Cancer Center scientists have completed a comprehensive map of genetic mutations occurring in the second-most common form of brain cancer, oligodendroglioma. The findings, reported in the August 4 issue of Science, also appear to reveal the biological cause of the tumors.
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