Varicella-zoster virus infections of the nervous system

Introduction
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By Catherine Amlie-Lefond MD and Burk Jubelt MD

Varicella-zoster virus infections of the nervous system is also known as Herpes zoster and Shingles. -ed.

Varicella-zoster virus causes chickenpox (varicella) in childhood, becomes latent in dorsal root ganglia, and can reactivate years later to produce shingles (zoster) in adults, as well as postherpetic neuralgia, central nervous system vasculopathy, myelitis, and meningoencephalitis. Diagnosis of varicella-zoster virus infection of the central and peripheral nervous system is critical as antiviral therapy can suppress productive infection with clinical benefit.

 

In This Article

Introduction
Historical note and nomenclature
Clinical manifestations
Etiology
Pathogenesis and pathophysiology
Epidemiology
Prevention
Differential diagnosis
Diagnostic workup
Prognosis and complications
Management
Pregnancy
References cited
Contributors