Tuberous sclerosis complex (TSC) is also known as or subsumes Bourneville disease, Diffuse cortical histioatypia, and Pringle disease. -ed.
Recent recommendations of the International TSC Consensus Conference for diagnosis, surveillance, and management of common clinical features of tuberous sclerosis complex are detailed.
Tuberous Sclerosis is a neurocutaneous disorder with significant neurologic implications, especially with regards to epilepsy and cognition.
Autism is a known manifestation of this disease.
Significant progress has occurred in the last few years in management of the clinical features of the disease based on advances in understanding of the pathogenesis and pathophysiology.