Transverse myelitis

Pregnancy
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By Anthony T Reder MD

No epidemiologic studies have been done. However, it would be expected that just as in multiple sclerosis, the normal immunosuppression of pregnancy would make transverse myelitis less likely during pregnancy, but more likely for a few months after delivery.

Women with preexisting transverse myelitis can have successful deliveries, but are subject to complications such as skeletal muscle fatigue, which depend on the severity of their neurologic disease (Berghella et al 1996). Systemic lupus erythematosus can mimic transverse myelitis, and exacerbations of systemic lupus erythematosus sometimes occur during pregnancy (Marabani et al 1989).

Drugs used for in vitro fertilization trigger attacks of multiple sclerosis. Buserelin, a gonadotropin-releasing hormone agonist, decreases the release of the luteinizing hormone and follicular stimulating hormone. It induced an attack of acute transverse myelitis 2 weeks after injections.

In This Article

Introduction
Historical note and nomenclature
Clinical manifestations
Clinical vignette
Etiology
Pathogenesis and pathophysiology
Epidemiology
Prevention
Differential diagnosis
Diagnostic workup
Prognosis and complications
Management
Pregnancy
Anesthesia
References cited
Contributors