Tardive dystonia

Historical note and nomenclature
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By L Giselle Aguilar Tábora MD

The first cases of tardive dystonia were described in the 1950s shortly after dopamine receptor antagonists were introduced. Keegan and Rajput described these dystonic movements as dystonia tarda (Keegan and Rajput 1973), but it was not until 1982 that Burke and colleagues first distinguished patients with tardive dystonia on phenomenological, epidemiological, prognostic, and pharmacologic grounds (Burke et al 1982).