Parkinson disease is also known as or subsumes Idiopathic parkinsonism, Paralysis agitans, and Shaking palsy. -ed.
Parkinson disease is one of the most common movement disorders that can be a challenge to diagnose and treat. In this clinical article, Dr. Samuel Frank, Associate Professor of Neurology at Boston University, provides an introduction to the clinical features, etiology, pathophysiology, epidemiology, and differential diagnosis of Parkinson disease. He reviews current medical therapies and treatment strategies in managing early and later stages of Parkinson disease. There is a summary of surgical interventions, including deep-brain stimulation, gene therapies, and cell-based transplant strategies. Although Parkinson disease is a chronic progressive neurodegenerative disease, there is hope for slowing the progression of the disease; using current clinical management strategies, patients can live longer and function better with their disease.