Neuroacanthocytosis is also known as or subsumes Choreoacanthocytosis and McLeod syndrome. -ed.
Neuroacanthocytosis is a neurologic disorder characterized by both a broad spectrum of movement disorders and acanthocytes seen in peripheral blood smear. Behavioral and cognitive disturbances are common features. An autosomal recessive form and an X-linked form of inheritance have been described and present similar phenotypes with characteristic features. Neuroacanthocytosis must be considered in the differential diagnosis of patients presenting with movement disorders and behavioral/cognitive findings. Treatments, including deep brain stimulation, are met with various levels of success.