Migraine: psychiatric comorbidities

Introduction
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By Chaichana Nimnuan MD PhD and Anan Srikiatkhachorn MD

Psychiatric conditions, especially mood, anxiety, and personality disorders, are common in persons suffering from migraine. These psychiatric comorbidities can alter the clinical course of migraine, its prognosis, and the quality of life of the sufferers. Therefore, diagnosis and treatment of these coexisting conditions are crucial parts of managing persons with migraine. In this clinical article, Dr. Chaichana Nimnuan and Dr. Anan Srikiatkhachorn of Chulalongkorn University review the recent findings as well as summarize the key concept of the association between migraine and these psychiatric conditions.

Key points

  • The psychiatric conditions coinciding with migraine can be classified into 3 main categories: mood disorders, anxiety disorders, and personality disorders.
  • The onset of depression either preceding or following migraine is common in patients with migraine.
  • Shared genetic vulnerability is the most likely explanation for migraine and comorbid depression.

In This Article

Introduction
Historical note and nomenclature
Clinical manifestations
Clinical vignette
Etiology
Pathogenesis and pathophysiology
Epidemiology
Prevention
Differential diagnosis
Diagnostic workup
Prognosis and complications
Management
References cited
Contributors