Intrathecal baclofen

Historical note and nomenclature
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By K K Jain MD

Baclofen has been the most widely used spasmolytic drug for the past 25 years. For about a decade, the intrathecal route has become the preferred mode of delivery of baclofen. This product was approved by the Food and Drug Administration in the United States in 1996.

In This Article

Historical note and nomenclature
Pharmacology
Clinical trials
Indications
Contraindications
Goals and duration of treatment
Dosing
Special considerations
Interactions
Adverse effects
References cited
Contributors