Hemorrhagic transformation of ischemic stroke

Introduction
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By Nivedita U Jerath MD and Chandan Reddy MD

Hemorrhagic transformation of ischemic stroke is also known as or subsumes Parenchymatous hematoma. -ed.

Hemorrhagic transformation after ischemic stroke is an often underdiagnosed phenomenon. With increasing and widespread use of tPA and with improved imaging capabilities afforded by newer sequences on MRI, it's now possible to predict which patients might be at increased risk of clinically significant hemorrhagic transformation. In this clinical article, the authors have added information about the risk of hemorrhagic transformation with tPA, the use of minocycline to decrease risk of hemorrhagic transformation, and the predictive value of hemorrhagic transformation in long-term prognosis.

In This Article

Introduction
Historical note and nomenclature
Clinical manifestations
Clinical vignette
Etiology
Pathogenesis and pathophysiology
Epidemiology
Prevention and risk factors
Differential diagnosis
Diagnostic workup
Prognosis and complications
Management
Pregnancy
Anesthesia
References cited
Contributors