Drug-induced seizures

Introduction
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By K K Jain MD

Key Points

  • Seizures can occur as an adverse effect of a large number of drugs from different pharmacological categories.
  • No characteristic clinical features differentiate drug-induced seizures from idiopathic epileptic seizures.
  • Use of drugs known to cause seizures should be avoided in patients with predisposition to seizures.
  • Most drug-induced seizures resolve after discontinuation of the offending drugs, but some patients require supplementary treatment.
  • Intravenous diazepam is the most frequently used drug for the control of drug-induced seizures.

In This Article

Introduction
Historical note and nomenclature
Clinical manifestations
Etiology
Pathogenesis and pathophysiology
Epidemiology
Prevention
Differential diagnosis
Diagnostic workup
Prognosis and complications
Management
Pregnancy
References cited
Contributors