Brain tumors in infancy and early childhood are also known as or subsume Congenital brain tumors, Connatal brain tumors, Infantile brain tumors, and Primitive brain tumors. -ed.
Approximately 10% to 15% of all childhood brain tumors will arise in the first 2 years of life. These tumors, which may be congenital, range from benign complex lesions that can be difficult to classify to highly malignant tumors that are often unresponsive to treatment. Embryonal tumors often arise in children younger than 2 years of age, and in the past decade an increasing incidence of the atypical teratoid/rhabdoid tumor has been reported. Although outcome is far from optimal, increasing evidence indicates that some subgroups of childhood infantile brain tumors have a somewhat better prognosis. Dr. Roger Packer from Children’s National Medical Center reviews current concepts of treatment for these diverse lesions, including the use of molecularly targeted therapy and novel radiation therapy techniques.