Researchers unravel mechanism that plays key role in sexual differentiation of brain
Mar 31, 2015
During prenatal development, the brains of most animals, including humans, develop specifically male or female characteristics. In most species, some portions of male and female brains are a different size, and may have a different number of neurons and synapses. However, scientists have known little about the details of how this differentiation occurs. Now, a new study by researchers at the University of Maryland School of Medicine has illuminated details about this process.
Researchers find promising new biomarkers for concussion
Mar 24, 2015
By looking at the molecular aftermath of concussion in an unusual way, a team of researchers at Brown University and the Lifespan health system has developed a candidate panel of blood biomarkers that can accurately signal mild traumatic brain injury within hours using standard, widely available lab arrays. The results appear in a new study in the Journal of Neurotrauma.
Magnetic brain stimulation
Mar 12, 2015
Researchers at MIT have developed a method to stimulate brain tissue using external magnetic fields and injected magnetic nanoparticles—a technique allowing direct stimulation of neurons, which could be an effective treatment for a variety of neurologic diseases, without the need for implants or external connections.
New Alzheimer-related memory disorder identified
Nov 14, 2014
A multi-institutional study has defined and established criteria for a new neurologic disease closely resembling Alzheimer disease called primary age-related tauopathy (PART). Patients with PART develop cognitive impairment that can be indistinguishable from Alzheimer disease, but they lack amyloid plaques. Awareness of this neurologic disease will help doctors diagnose and develop more effective treatments for patients with different types of memory impairment.
tPA’s tardy twin could aid in stroke recovery
Oct 22, 2014
Study findings suggest that in stroke, uPA's (urokinase-type plasminogen activator) benefits may extend beyond the time when doctors' principal goal is dissolving the blood clot that is depriving the brain of blood. Instead, uPA appears to help brain cells recover from the injuries induced by loss of blood flow. Treating mice with uPA after an experimental stroke can improve their recovery of motor function, the researchers found.
AAN: Risks of opioids outweigh benefits for headache, low back pain, other conditions
Sep 30, 2014
According to a new position statement from the American Academy of Neurology (AAN), the risk of death, overdose, addiction, or serious side effects with prescription opioids outweigh the benefits in chronic, non-cancer conditions such as headache, fibromyalgia, and chronic low back pain. The position paper is published in the September 30, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.